2nd pediatric case April 2025 - We are pleased to share the second publication in our ongoing series of pediatric CML (pCML) case reviews from low and middle-income countries (LMICs). These cases reflect the complexities inherent in managing pCML in resource-limited settings and aim to provide a comprehensive discussion from various perspectives to enhance knowledge and improve patient outcomes.

The latest case, published in the March edition of Case Reports in Oncology Medicine, highlights a challenging case from Brazil. Experts discuss treatment discontinuation in a child with CML who has not achieved a sustained deep molecular response.

March 2025 - Every year, the iCMLf Prizes acknowledge individuals whose remarkable contributions have shaped the field of CML, driving progress in research, treatment, and care worldwide. This year, we celebrate three outstanding people whose work has transformed our understanding of CML biology, refined clinical management, and improved CML treatment and care in low- and middle-income countries.

We are delighted to announce the recipients of the 2025 iCMLf Prizes:

Rowley Prize – Professor Satu Mustjoki (Finland)
Goldman Prize – Dr. Delphine Rea (France)
iCMLf Prize – Professor Nicholas Anthony Othieno-Abinya (Kenya)

Twenty-five years ago, the landscape of chronic myeloid leukemia (CML) treatment changed forever with the introduction of tyrosine kinase inhibitors (TKIs). Before this breakthrough, CML was a life-threatening diagnosis, with limited treatment options such as interferon therapy or bone marrow transplantation. Today, thanks to TKIs, CML has transformed into a manageable condition, allowing patients to live full and productive lives.

We are pleased to announce the first instalment of our 2025 South Asian regional program to address specific local challenges for physicians treating people with CML. We are starting this year's progam of three zoom-based Regional Discussion Groups on April 23rd.

We are pleased to announce the first instalment of our 2025 Latin American regional program to address specific local challenges for physicians treating people with CML. We are starting this year's progam of three zoom-based Regional Discussion Groups on May 8th.

Are you ready for an unforgettable adventure that makes a difference?

Building on the success of Climb for a Cure: Kilimanjaro (2019) and Annapurna (2023) - which together raised over $500,000 for CML research - the iCMLf is thrilled to announce the next chapter: Climb for a Cure 2026.

In February 2026, we will take on the Avenue of Volcanoes in Ecuador - a breathtaking high-altitude challenge through one of the most stunning landscapes in the world. Over seven days, participants will trek through Cotopaxi National Park, climb to awe-inspiring viewpoints, and push their limits alongside a passionate team of researchers, doctors, patients, and CML advocates - all united by a single goal: drive progress in CML research, treatment, and patient care.

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