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Science & Education
CML Science News
Clinical reality in CML is in constant change. Thanks to the hard work and progress of clinicians and researchers worldwide, interesting updates on CML science, diagnostics, treatment and care are regularly presented at international meetings and published in leading peer-reviewed journals.
This section provides you with a selection of scientific publications on CML, relevant news from scientific meetings and expert opinions from leaders in the field. You will also find links to active CML clinical trials.
CML publications
Please find below a selection of interesting articles on CML from peer-reviewed journals. Recent publications include:
Clinical CML papers
- Olverembatinib after failure of tyrosine kinase inhibitors, including ponatinib and asciminib: A phase 1b randomized clinical trial
Jabbour E et al. JAMA Oncol, November 2024 (epub ahead of print) - Asciminib monotherapy as frontline treatment of chronic-phase chronic myeloid leukemia: results from the ASCEND Study
Yeung DT et al. Blood, November 2024 - Long-term outcomes of tyrosine kinase inhibitors in chronic myeloid leukemia
Guilhot F and Hehlmann R. Blood, November 2024 (epub ahead of print) - Dose modifications in the management of chronic phase chronic myeloid leukemia: Who, what, and when - Review
Oehler VG et al. J Natl. Compr Canc Netw, November 2024 – open access publication - Loss in overall and quality-adjusted life expectancy for patients with chronic-phase chronic myeloid leukemia
Chen EY et al. Eur J Haematol, November 2024 (epub ahead of print) – open access publication - Real-world toxicity and efficacy of asciminib in heavily pretreated patients with chronic myeloid leukemia
Ishii Y et al. Int J Haematol, November 2024 (epub ahead of print) - Clinical outcomes in patients in any phase of CML treated with ponatinib in France-Data from the TOPASE Observational Study
Huguet F et al. Br J Haematol, November 2024 (epub ahead of print) – open access publication - Comparing de novo chronic myeloid leukemia in blastic phase with Philadelphia chromosome-positive acute lymphoblastic leukemia after allogeneic hematopoietic cell transplantation
Okada Y et al. Cancer, November 2024 (epub ahead of print) - Myelofibrosis predicts deep molecular response 4.5 in chronic myeloid leukemia patients initially treated with imatinib: An extensive, multicentred and retrospective study to develop a prognostic model
Zeng T et al. Clin Trans Med, November 2024 – open access publication - Decitabine, venetoclax, and ponatinib for advanced phase chronic myeloid leukemia and Philadelphia chromosome-positive acute myeloid leukemia:
A Single arm, single centre phase 2 trial
Short NJ et al. Lancet Haematol, November 2024
Scientific CML papers
- Single-cell multiomics analysis of chronic myeloid leukemia links cellular heterogeneity to therapy response
Warfvinge R et al. eLife, November 2024 – open access publication - Immune checkpoints PD1/PDL1, TIM3/GAL9 and key immune mediators landscape reveal differential expression dynamics on imatinib response in chronic myeloid leukemia
Toloza MY et al. Ann Hematol, November 2024 (epub ahead of print) - A novel next generation sequencing assay for the identification of BCR::ABL1 transcript type and accurate and sensitive detection of TKI-resistant mutations
Yan Z et al. J Appl Lab Med, November 2024 - The CML experience to elucidate the role of innate T-cells as effectors in the control of residual cancer cells and as potential targets for cancer therapy
Decroos A. et al. Front Immunol, November 2024 – open access publication
CML Congress Materials
European Hematology Association (EHA) 2024 Hybrid Congress
13-16 June, 2024 - Madrid
Click here to access the EHA Library and find oral presentations, e-Posters and abstracts on CML:
- Oral presentations - biology & translational research
- Oral presentations - clinical
- e-Posters - biology & translational research
- e-Posters - clinical
- Poster presentations - biology & translational research
- Poster presentations - clinical
- For publication only - biology & translational research
- For publication only - clinical
Ongoing clinical trials on CML
Search here for CML clinical trials:
Advances from key CML publications
This independent educational resource was provided over the last couple of months as a special service by the iCMLf in partnership with Springer Healthcare IME and is supported by a grant from Novartis Oncology.
Stories are based on articles published in international peer-reviewed journals, or conference sessions and written by highly experienced and knowledgeable writers.
You can access the CML stories from previous months here
