Read Professor Hughes' summaries of key CML publications

This series of paper summaries is an extension of Professor Tim Hughes' 'CML publications of the month' news service.
These summaries, selected and curated by Professor Hughes, will be compiled and provided every three months, offering a comprehensive overview of key CML papers. This approach ensures that clinicians, researchers, and healthcare professionals stay up-to-date with important pivotal studies and emerging trends in CML research.

CML paper highlight #1  - July 2024: Asciminib in newly diagnosed CML (Hochhaus A et al. NEJM, May 2024)
Link to full paper (ClinicalTrials.gov no. NCT04971226)

The ASC4FIRST study published in the New England Journal of medicine serves as the first example in this series. This phase 3 trial investigates the efficacy and safety of asciminib compared to established tyrosine kinase inhibitors (TKIs) in the first-line treatment of chronic-phase CML. 

View the paper summary here