The iCMLf Forum, held on December 7th during the American Society of Hematology meeting in San Diego,  brought together leading clinicians, researchers, and patient advocates  to explore groundbreaking advancements in the pursuit of treatment-free remission (TFR) for patients with CML. This year’s Forum focused on Advancing TFR globally, overcoming the barriers in LMICs and looking to the future of potential biomarkers along with the biological barriers to cure CML.

Professor Jorge Cortes opened the event, setting the tone for discussions by underscoring the iCMLf’s commitment to bridging the gap between scientific progress and practical implementation. “Together, we aim to make TFR a reality for all, regardless of geography or economic circumstances,” he emphasised.

The Forum opened with a powerful exploration of the biological and logistical challenges in achieving a true cure for CML. Professor Brian Druker highlighted the complexities of residual disease, while Professor Ong Sin Tiong presented cutting-edge biomarkers poised to transform patient selection for TFR. Dr Katia Pagnano chaired an insightful session on pathways to successful TFR, delving into monitoring strategies and the essential role of patient support systems. Discussions also focused on overcoming inequities in LMICs, with contributions from Dr Naranie Shanmuganathan and Professor Biswas, who shared practical strategies for improving diagnostic and monitoring infrastructure in resource-limited settings.

The urgency of advancing diagnostic tools and robust monitoring strategies took center stage, with Professor Jerry Radich emphasising their importance in ensuring patient safety and long-term success. The event concluded with a collaborative panel discussion, moderated by Giora Sharf, addressing innovation, equity in global CML care, and the need for international cooperation. Together, these sessions underscored the shared commitment to improving outcomes and paving the way for a future where TFR is achievable for all.

For a detailed summary of the iCMLf Forum 2024, including session highlights and expert insights, read a full summary here.

The iCMLf continues to drive progress by bringing together the brightest minds in CML research and management. Events like the Forum are a testament to the global community’s shared commitment to improving outcomes and moving closer to a world where treatment-free remission is achievable for all.