The 2019 Goldman Prize is awarded to Professor François-Xavier Mahon

The iCMLf awards the 2019 Goldman Prize to Professor François-Xavier Mahon, Director of the Cancer Center of Bordeaux (Bergonie Institute) in recognition of his breakthrough achievements in the clinical development of CML therapies and his pioneering research on treatment discontinuation in CML. The annual Goldman Prize awarded in honour of Professor John Goldman, acknowledges outstanding lifetime contributions to the management of patients with CML.

François-Xavier Mahon was amongst the first to explore treatment-free-remission (TFR) and his work was instrumental in advancing the discussion on treatment discontinuation by providing solid scientific evidence. He is internationally recognised for initiating and leading the clinical trials that first showed a proportion of highly tyrosine kinase inhibitor (TKI)-responsive chronic phase CML patients can be sustained in remission after discontinuation of therapy.

Professor Mahon was key investigator for the STIM-trial and has been involved in numerous other pioneering treatment discontinuation studies that validated the concept of TFR and evaluated the ability to maintain a molecular response after stopping therapy, including EURO-SKI and STOP 2G-TKI. With his work he has helped to introduce the concept of TKI discontinuation and prepared the ground for the next step to come addressing the topic of cure in CML.

Since 2016 Professor Mahon is Director of the Cancer Center of Bordeaux (Bergonie Institute) and currently serves as the President of the French Group of CML (FI-LMC). Before taking over his current position he served as a Professor of Hematology and Medical Biology, Director of the Hematology Laboratory and Senior House Physician at the University in Bordeaux, France. He graduated in clinical haematology from the Faculty of Medicine, University of Bordeaux and received his PhD for the work on the topic ‘Selection of normal cells in chronic myeloid leukaemia’. Professor Mahon completed a research fellowship at the Imperial College of London. He has authored or co-authored more than 210 articles in peer-reviewed journals.

Learn more about Francois-Xavier Mahon here