November 2021 - We continue our 'From the laboratory' series on the iCMLf Knowledge Centre with a new module for clinicians that will increase your knowledge on diagnosis and testing methods.

Module 4 is a series of talks that will take you on the journey with your patients from diagnosis to monitoring response and the role of genomic mutation screening. Starting with the main laboratory studies at diagnosis, you’ll then learn how to best monitor your patients over time and what are the critical milestones.

Other presentations will give an overview of mutation testing in case of relapse or resistance, how to interpret results and what to do clinically when your patients have certain mutations. Another presentation focuses on mutations other than BCR-ABL, how often they occur and conclusions for clinical practice.

As always, we have put a spotlight on the needs of physicians treating CML patients in the emerging regions, specifically solutions for diagnosis and testing in a resource-constrained setting.

Learn more in a short video overview from Professor Jerry Radich, who co-chairs this module together with Dr Carolina Pavlovsky from Argentina.

iCMLf Knowledge Centre  - ‘From the Laboratory – For Clinicians

The fourth module outlines current and future diagnosis and testing methods from the perspective of clinicians:

• CML - Main laboratory studies at diagnosis
  Dr Carolina Pavlovsky (FUNDALEU, Buenos Aires /Argentina)
• Optimal test frequency for MRD
  Dr Carolina Pavlovsky (FUNDALEU, Buenos Aires /Argentina)
• Clinical data to support each treatment milestone
  Dr Kendra Sweet (Moffitt Cancer Center, Tampa /USA)
• Essential molecular monitoring (focusing on LMICs)
  Professor Jerry Radich (Fred Hutchinson Cancer Research Center,
  Seattle, USA)
• When BCR-ABL1 mutation testing is recommended
  Dr Simona Soverini (University of Bologna, Bologna/Italy)
• The role of genomic analysis and panel mutation screening
  Professor Michael W. Deininger (Medical College of Wisconsin /
  Versity Blood Research Institute, Milwaukee/USA)

Access all presentations of module 4 here

If you have any questions or comments on the presentations for the speakers or the community, you can leave a comment on the discussion section.

We kindly thank all experts of this third module for their valuable contribution and Novartis Oncology for the support that made this program possible.

We hope that this module will provide you with a good overview of laboratory testing and help you in your clinical practice.

Your comments are welcome!