Ricardo Pasquini

Universidade Federal do Paraná
Curitiba, Brazil

Ricardo Pasquini is an Emeritus Professor of Internal Medicine, Hematology and Oncology and former Head of the Division of Hematology and Medical Oncology at Hospital de Clínicas of Federal University of Paraná in Curitiba, Brazil and also Head of Bone Marrow Transplant Center at the same Institution for almost 30 years.

He pioneered hematopoietic stem cell transplant in Latin America, doing the first transplant in 1979 and more than 1800 procedures, mainly allogeneic, were performed. The major experience in stem cell transplant concentrated in CML and acquired and constitutional Aplastic Anemias patients. Following the advent of TKIs inhibitors (year 2000), he organized and coordinated a CML outpatient clinic where approximately 400 patients have been registered and some enrolled in several protocols. Also, a laboratory for BCR/ABL quantification and mutation detection was settled that receive samples from several Brazilian Centers.

He has been interested in treatment optimization of chronic myelogenous leukemia (CML) and has been involved in the management of the randomized CML Studies I-IV of the German CML Study Group for more than 19 years. His special interests are the molecular monitoring of minimal residual disease and mechanisms of resistance in CML, and targeted therapy in a variety of neoplastic disorders.

Dr. Pasquini is investigator for the nilotinib, dasatinib and bosutinib phase II and phase III studies, has been participating in imatinib phase II and III studies and is a member of World CML Advisory Committee.

He is a member of the American Society of Hematology (member of the International members Committee for nine years), the European Hematology Association, the American Society of Clinical Oncology, the International Society of Experimental Hematology, the American Society of Blood and Marrow transplant and for many years member of the Executive and Advisory Committee o IBMTR/CIBMTR. He is a member of the Brazilian Hematology Association and founder member of the Brazilian Bone Marrow Transplant Society. He has published over 100 peer-reviewed papers and is regularly invited to speak at national and international symposia.