The importance of BCR-ABL kinase domain mutation analysis in CML
Susan Branford, University of Adelaide, Australia
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Issues covered
Mutations as a mechanism of imatinib resistance
Why mutations arise
When to test for mutations
Therapeutic options in the presence of mutations
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Facteur de variabilité de la réponse au ITK</li> <li>Les trois grand mécanismes de résistance</li> <li>La réponse au traitement</li> <li>Autres inhibiteurs de tyrosine kinase: le Nilotinib et le Dasatinib