May 2022 - Our continuous commitment as a Foundation is to support the CML community with reliable up to date information about COVID-19 and CML – even now, in the third year of the pandemic.

Questions about CML management during the COVID-19 pandemic remain highly relevant for clinical practice. In particular, whether COVID-19 vaccines are recommended and effective for people with CML.

To provide you with the best possible support, the iCMLf continues to update our COVID-19 Hub with CML specific information on COVID-19. We are also sharing an updated statement on COVID-19 vaccines for people with CML. You can read the full statement below:

It's great to be back in person at the 2022 Congress of the European Hematology Association. The congress is being held as a hybrid meeting in Vienna and online from June 9-17, 2022:

June 9-12: Live streamed program
June 15-17: Virtual thematic days

To help you plan your CML meeting schedule at EHA we have compiled a list of CML related sessions for your convenience. You can look forward to an exciting scientific program and a highlight from the iCMLf: A first sub-analysis of the iCMLf CML and COVID-19 CANDID data will be presented as a clinical poster during EHA.

We are looking forward to seeing you live in Vienna or online!

May 2022 - We are pleased to announce that the latest module of the iCMLf Knowledge Centre – ‘Management Practicalities’ – will be rolled out in two tranches with the first set of presentations now available.

Module 5 is a series of talks that will feature various topics on the practical management of CML to help you in your clinical practice.

Topics include; managing intolerances and relevant comorbidities, TKI interactions and adverse events. This highly practical module is chaired by Professor Giuseppe Saglio (Italy) and Professor Mohamed Yassin (Qatar).

May 2022 - Questions about CML management during the COVID-19 pandemic remain highly relevant for clinical practice. To provide physicians treating CML around the world with best possible support, we are hosting expert talks on CML and COVID-19 management in French, Portuguese, Spanish and Russian.

If you speak Portuguese, join us for the live expert talk in Portuguese on May 31st at 8.30 AM Brazilian Time with Dr Katia Pagnano from Brazil. You will learn how to best treat your patients with CML and COVID-19 and get the latest updates on COVID-19 vaccines for patients with CML.

As a reminder the presentation on COVID-19 and CML in French is available here

April 2022 - We are delighted to share that a first sub-analysis of the iCMLf CML and COVID-19 CANDID data has been accepted as a clinical poster presentation for the EHA 2022 Congress in June:

COVID-19 in patients with chronic myeloid leukemia in treatment-free remission:
Disease-severity and impact on TFR status (Saußele S et al. EHA 2022 abstract no. 1886)

The sub-analysis of the CANDID study aimed to evaluate the outcome of SARS-CoV-2 infection in CML patients in treatment-free remission and assessed any impact on maintenance of TFR. Additional information were collected for this analysis including: molecular remission status before, during and after COVID-19 infection.

We look forward to seeing you at EHA and sharing more details.

April 2022 - The iCMLf Genomics Alliance is now partnering with the HARMONY Big Data platform to analyse genetic data from thousands of CML patients. A novel iCMLf Genomics Alliance research project, led by Professor Thomas Ernst (University Hospital Jena, Germany) will study the role of genetic aberrations in the disease course of CML.

'A goal of the iCMLf Genomics Alliance is to pool mutatational data through a shared database. This will enhance statistical power in order to understand the impact of genomic variation on treatment response for patients with CML' (Sue Branford – Chair of the iCMLf Genomics Alliance)

The iCMLf is leading the way to bring the CML community together to contribute genomic and clinical data to the HARMONY Plus database and use ‘Big Data’ to answer key questions in CML. The first project aims to elucidate the hierarchy of genomic events that underlie the disease course in CML. Sites from Australia, Canada, Czech Republic, Germany, Italy, Russia, Spain, Taiwan, UK and USA are currently entering data for the project.

We welcome further interest from groups to contribute data, or ideas for future analysis.

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